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Home > Products > Pharmaceutical Material > Pharmaceutical Intermediates > DL-Gossypol Methanoic Acid CAS 12542-36-8 Gossypol Acetate Online
DL-Gossypol Methanoic Acid CAS 12542-36-8 Gossypol Acetate Online
  • DL-Gossypol Methanoic Acid CAS 12542-36-8 Gossypol Acetate Online

DL-Gossypol Methanoic Acid CAS 12542-36-8 Gossypol Acetate Online

    Payment Type: L/C,T/T,D/P,Paypal,Money Gram,Western Union
    Incoterm: FOB,CFR,CIF,EXW,FCA,CPT,CIP
    Min. Order: 10 Gram
    Delivery Time: 7 Days
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Basic Info

Model No.: TF2010

Additional Info

Packaging: As Buyer's Request

Productivity: 100Ton

Brand: Tianfu

Transportation: Ocean,Land,Air,DHL,TNT

Place of Origin: China

Supply Ability: 50Ton

Certificate: ISO

Port: Shanghai port,Qingdao port

Product Description

About the Gossypol Acetate

1, gossypol acetate on the regulation of ovarian hormones has a certain role.
Is mainly for hormone receptor inhibition at early stage, patients can reduce abnormal vaginal estrogen levels, but the serum estradiol, progesterone levels before and after ovulation had no effect.After a period of treatment, the serum hormone level decreased, but the natural recovery after the drug was stopped, does not affect fertility function.


2, the original secondary dysmenorrhea treatment effect
Gossypol acetic acid can inhibit the activity of lysosomal and the synthesis of DNA, which makes arachidonic acid into prostaglandins, this step is blocked, can inhibit the synthesis of prostaglandin and thrombosis.ACTS on the endometrium, can reduce endometrium metabolites prostaglandins and thromboxane in 6 - ketone - PGF1 alpha, TXB2 a significant therapeutic effect.
Compound gossypol acetate film contains vitamin B6, the use of vitamin B6 promote magnesium ions (mg++) through the cell membrane, increase the intracytoplasmic mg++ concentration effect, so as to play to the treatment of primary dysmenorrhea.


3. High concentrations of gossypol, function of enzyme or protein related cell growth, cell apoptosis, but not malignant hyperplasia induced cells


4.Gossypol acetic acid can make endometrial estrogen and progesterone in the dependence of acid phosphatase (ACP), nonspecific lipase (NSE) and alkaline phosphatase (AKP) activity decline, have indirect inhibition of endometrial cells.

5, inhibition of DNA synthesis of endometrial cells
Gossypol acetic acid can inhibit endometrial cells thymine and DNA synthesis, thereby directly inhibit the growth of endometrium atrophy.
High concentrations of gaa enzyme or functional protein can be related to cell growth, cell apoptosis, but not malignant hyperplasia induced cells.


Standard specifications (CERTIFICATION OF ANALYSIS)

Item

Specification

Method Result

General Analysis

Gossypol acetate 98%

Assay(Gossypol-acetic acid)

Identification

Loss on Drying

98%

Identical to R.S. sample

≤5.0%

HPLC

HPLC

Eur.Ph.6.0[2.8.17]

Conforms

Conforms

3.16%

Ash

≤5.0%

Eur.Ph.6.0[2.4.16] 3.52%

Contaminants

Solvents Residue

Meet Eur.Ph6.0<5.4>

Eur.Ph 6.0<2.4.24> Conforms

Pesticides Residue

Meet USP32<561>

USP32<561> Conforms

Lead(Pb)

≤3.0mg/kg

Eur.Ph6.0<2.2.58>ICP-MS 2.45

Arsenic(As)

≤2.0mg/kg

Eur.Ph6.0<2.2.58>ICP-MS 1.29

Cadmium(Cd)

≤1.0mg/kg

Eur.Ph6.0<2.2.58>ICP-MS 0.68

Mercury(Hg)

≤0.1mg/kg

Eur.Ph6.0<2.2.58>ICP-MS 0.07

Microbiological

Total Plate Count

≤1000cfu/g

USP30<61> 120

Yeast &Mold

≤100cfu/g

USP30<61> 51

E.Coli.

Negative

USP30<62> Conforms

Salmonella

Negative

USP30<62> Conforms


CAS 12542-36-8 in Stock

Looking for ideal Gossypol Acetate Online Manufacturer & supplier ? We have a wide selection at great prices to help you get creative. All the DL-Gossypol Methanoic Acid for Sale are quality guaranteed. We are China Origin Factory of CAS 12542-36-8 in Stock. If you have any question, please feel free to contact us.

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